绝经前女性的维生素D,铁和肝素之间的关系,可能因种族而混
Anya Greenwood1, Pamela Ruth von Hurst1, Kathryn Louise Beck1
1School of Sport, Exercise and Nutrition, Massey University Auckland, Auckland, New Zealand.
European journal of nutrition
|August 29, 2023
概括
维生素D和肝素水平在绝经前妇女中显示出不同族群与铁状况的不同关联. 南亚妇女在维生素D和肝素之间呈现出意想不到的积极联系,这可能是由于炎症和身体脂肪的增加.
科学领域:
- 营养生物化学与人类健康.
- 跨文化健康差异 跨文化健康差异
背景情况:
- 维生素D和肝素在调节铁平衡中起着至关重要的作用.
- 维生素D和铁状况的种族差异已得到充分证实.
- 了解这些关系对于公共卫生倡议至关重要.
研究的目的:
- 为了研究维生素D,肝素和铁状况之间的关联.
- 为了检查这些协会跨不同种族队伍在绝经前女性.
- 探索维生素D和铁代谢的潜在种族特异性差异.
主要方法:
- 一项涉及160名来自奥克兰新西兰不同种族背景的绝经前女性 (18-45岁) 的横截面研究.
- 测量包括人口统计,身体组成,血清25(OH) D,炎症标记物 (CRP,IL-6) 和铁生物标记物 (费里丁,血红蛋白,TfR,肝素).
- 统计分析包括ANOVA,Kruskal-Wallis,Chi-squared测试和ANCOVA来比较群体和协会.
主要成果:
- 与新西兰欧洲人相比,南亚参与者身体脂肪百分比和IL-6水平较高,25...OH) D度较低.
- 在新西兰欧洲人中,较高的25~OH) D与较低的肝素水平有关.
- 在南亚妇女中观察到25 ((OH) D和肝素之间的意想不到的积极关联.
结论:
- 在南亚妇女中观察到的维生素D和肝素之间的积极关系可能受到较高的IL-6,体脂和较低的维生素D水平的影响.
- 这些发现突出了维生素D,肝素和铁状况之间的潜在种族特异性相互作用.
- 需要进一步的研究来证实这些种族特异性观察.
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