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Updated: Jul 17, 2025

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages
06:52

Detection of Inflammasome Activation and Pyroptotic Cell Death in Murine Bone Marrow-derived Macrophages

Published on: May 21, 2018

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菌毒素激活了核毒性压力和NLRP1炎症酶驱动的热灭菌

Kim Samirah Robinson1,2, Gee Ann Toh1, Muhammad Jasrie Firdaus1

  • 1Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.

The Journal of experimental medicine
|August 29, 2023
PubMed
概括

由ZAKα驱动的核糖毒性应激反应 (RSR) 和NLRP1炎症体感知细菌毒素,激活天生的免疫力. 抑制ZAKα可以保护皮肤免受白喉毒素的影响,这表明它在抗菌防御中起作用.

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