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Updated: Jul 17, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

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通过计算和基于细胞的研究,类素作为结构突变p53Y220C的潜在活性剂

Lakshay Malhotra1,2, Punit Kaur1, Abdul Samath Ethayathulla1

  • 1Department of Biophysics, All India Institute of Medical Sciences, New Delhi, India.

Journal of biomolecular structure & dynamics
|August 29, 2023
PubMed
概括

某些类黄,特别是MPA和MPB,可以恢复p53 Y220C癌症突变的功能. 这些化合物显示出稳定突变的p53蛋白的治疗潜力,可以用于癌症治疗.

关键词:
细胞毒性 细胞毒性黄类化合物 黄类化合物分子对接的分子对接.p53Y220C 这是一个很好的方法.胰腺癌是一种癌症.

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