在抗血管内生长因子治疗多冠状血管病的治疗后,焦点冠状血管挖掘的发展
Akinori Uemura1, Takuto Hamada, Naohisa Mihara
1Department of Ophthalmology, Kagoshima City Hospital, Kagoshima, Japan.
Retinal cases & brief reports
|August 29, 2023
概括
针对多性胆道血管病的静脉内抗血管内皮生长因子注射可以导致焦点胆道挖掘的发展. 本案例报告强调了在四年后续期间的一项新发现.
科学领域:
- 眼科医生 眼科 眼科
- 医学案例报告 病例报告
背景情况:
- 多性冠状血管病变 (PCV) 是一种与年龄相关的黄斑变性的一种亚型.
- 帕奇科罗伊德的特征与PCV有关,其特征是厚的胸膜.
研究的目的:
- 描述一个PCV病例与新开发的焦点胆道挖掘.
- 为了记录这次挖掘的4年进展.
- 为了将挖掘发展与抗VEGF治疗相关联.
主要方法:
- 案例报告方法论.
- 使用光学连贯断层扫描 (OCT) 和绿色血管扫描 (ICGA).
- 记录了为期4年的随访,包括连续成像和治疗记录.
主要成果:
- 一名64岁的男性被诊断患有PCV和帕奇科罗伊德特征.
- 最初的表现:20/20视力,RPE脱落,脑下液和ICGA上的多形病变.
- 在4年的时间里,抗VEGF注射导致RPE脱落缩小,并出现焦点胆道挖掘与内部胆道衰减.
结论:
- 针对PCV的抗VEGF疗法可能会导致多形损伤缩.
- 在相邻的内胆道血管中可能会出现血流减少.
- 这种血管变化与新型焦点胆道挖掘的形成有关.
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