埃塞俄比亚西达马地区本萨区杆菌病的决定因素:一个病例对照研究
Melaku Hailu1, Nana Chea2, Musa Mohammed Ali3
1Tulla Primary Hospital, Hawassa, Ethiopia.
PLoS neglected tropical diseases
|August 29, 2023
概括
一种被忽视的热带疾病 - - 脊髓灰质炎与性别,鞋履习惯和家族病史等因素有关. 早期使用鞋子和持续佩戴会降低风险,而某些类型的鞋子会增加风险.
科学领域:
- 皮肤病学 皮肤病学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 脊髓灰质炎是一种被忽视的热带疾病 (NTD),具有重大公共卫生影响,特别是在埃塞俄比亚.
- 关于其原因,预防和治疗的误解阻碍了控制工作.
- 全球有400多万人受到影响,埃塞俄比亚有150多万病例.
研究的目的:
- 鉴定埃塞俄比亚西达马地区邦萨区 (Bensa District, Sidama Regional State,Ethiopia) 脊柱病的关键决定因素.
- 为有针对性的公共卫生干预和疾病消除战略提供证据.
主要方法:
- 进行了一项基于社区的,无与伦比的病例控制研究.
- 从153个病例和306个对照中使用面试官管理的问卷收集数据.
- 多变量二进制物流回归分析确定了多孔病的显著风险因素.
主要成果:
- 显著相关的podoconiosis的因素包括参与者的年龄,女性性别,开始穿鞋的年龄,使用鞋的频率,鞋类 (硬塑料鞋) 的类型,以及腿部胀的家族史.
- 具体来说,女性 (AOR=2.90),每天不穿鞋 (AOR=2.26) 和穿硬塑料鞋 (AOR=3.38) 的风险增加,而较早开始穿鞋 (AOR=0.7) 和年龄较大降低了风险.
- 腿部胀的家族病史显示出强烈的关联 (AOR=10.2).
结论:
- 足病的决定因素包括人口因素,开始穿鞋的年龄,鞋类和鞋类的频率以及遗传倾向.
- 公共卫生倡议应侧重于宣传活动和教育,以保持一致的鞋履和足部卫生.
- 区域卫生局和非政府组织之间的合作对于消除病的努力至关重要.
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