医院环境中的杀菌剂:应用和耐受性发展
Catarina Geraldes1,2, Luís Tavares1,2, Solange Gil1,2,3
1Department of Animal Health, Centre for Interdisciplinary Research in Animal Health (CIISA), Faculty of Veterinary Medicine, University of Lisbon, Lisbon, Portugal.
概括
医院感染是一个越来越令人担忧的问题. 本审查审查了用于感染控制的化学生物制剂,重点关注影响有效性和耐药性发展的因素,以防止滥用抗微生物药物.
科学领域:
- 感染控制和医院流行病学
- 抗微生物耐药性 抗微生物耐药性
- 环境卫生环境卫生
背景情况:
- 医院感染 (HAI) 对患者,医疗机构和工作人员构成重大风险.
- 杀菌剂对于降低医院环境中的微生物负载至关重要,以预防HAI.
- 有效的生物制剂选择和应用对于感染控制至关重要.
研究的目的:
- 审查用于医院感染控制的化学生物制品.
- 分析影响生物制剂疗效的因素,包括度和有机物质.
- 解决生物制剂的滥用问题,防止抗菌素耐药性的发展.
主要方法:
- 对用于医院感染控制的化学生物制剂的文献综述.
- 对影响生物制剂有效性和微生物易感性的因素的分析.
- 讨论预防抗微生物药物耐药性的战略.
主要成果:
- 存在各种化学生物制剂组,每个都有特定的特性和应用.
- 杀菌剂的有效性受到有机物度和存在的显著影响.
- 不适当使用生物制剂可能导致敏感性和耐药性降低.
结论:
- 了解生物制剂特性和影响因素对于有效控制医院感染至关重要.
- 合理使用生物杀菌剂可以减轻HAI的风险,并制抗菌素耐药性.
- 需要进一步研究和教育生物制剂的应用,以优化其在医疗保健环境中的作用.
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