相关实验视频
Updated: Jul 17, 2025

08:46
A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
6.5K
在SARS-CoV-2感染和COVID-19疫苗接种后,新生儿和母亲的结局:基于人口的匹配队列研究
Laura Lindsay1, Clara Calvert2,3, Ting Shi2
1Public Health Scotland, Edinburgh, Scotland, UK.
Nature communications
|August 29, 2023
概括
怀孕期间的COVID-19感染增加了早产和关键母亲结果的风险. 然而,在怀孕期间接种COVID-19疫苗是安全的,可以保护母亲和婴儿免受这些不良影响.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 新生儿健康 新生儿健康
背景情况:
- 了解怀孕期间SARS-CoV-2感染和COVID-19疫苗接种的影响对于临床实践至关重要.
- 需要基于人口的数据来评估与流行病期间怀孕相关的风险.
研究的目的:
- 调查SARS-CoV-2感染与怀孕期间的COVID-19疫苗接种以及新生儿和母亲的不良结果之间的关联.
- 在COVID-19大流行期间,为有关怀孕管理的临床决策提供信息.
主要方法:
- 在苏格兰进行了一项全国性的,基于人口的,匹配的队列研究.
- 条件后勤回归被用来分析从单独怀孕的数据结束在≥20周的怀孕.
- 结果包括死产,新生儿死亡,早产,怀孕年龄小,低Apgar分数,孕妇重症监护入院或死亡,静脉血栓栓塞,高血压疾病和出血.
主要成果:
- 怀孕期间的SARS-CoV-2感染与早产 (aOR=1.36) 和非常早产 (aOR=1.90) 的风险增加有关.
- 感染还增加了母亲进入重症监护或死亡 (aOR=1.72) 和静脉血栓栓塞 (aOR=2.53) 的风险.
- 在怀孕期间接种COVID-19疫苗后,没有发现不良结果的风险增加.
结论:
- 怀孕期间的SARS-CoV-2感染与新生儿和母亲的不良健康结果有关.
- 怀孕期间接种COVID-19疫苗是一种安全有效的措施,可以保护孕妇及其新生儿免受感染相关的并发症.
相关概念视频
Bias in Epidemiological Studies
349
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
349
Teratogenicity
2.5K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.5K
Vaccinations
44.7K
Overview
44.7K
Factors Affecting the Risk of Infection
11.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K
Confounding in Epidemiological Studies
188
Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
188

