营养不良的风险及其对老年癌症患者的临床影响
Zehra Sucuoglu Isleyen1, Mehmet Besiroglu1, Ayse Irem Yasin1
1Department of Medical Oncology, Bezmialem Vakif University, Istanbul, Turkey.
Aging clinical and experimental research
|August 29, 2023
概括
老年癌症患者的营养不良风险很常见,并且与死亡率增加和老年综合征 (如虚弱和抑郁症) 相关. 早期诊断对于在老年瘤学中获得更好的结果至关重要.
科学领域:
- 老年瘤学 老年瘤学
- 营养科学 营养科学
- 在瘤学瘤学.
背景情况:
- 营养不良是一种普遍的老年综合征,具有显著的负面健康结果,包括死亡率.
- 关于营养不良风险与老年癌症患者临床影响之间的具体关系的研究有限.
研究的目的:
- 确定营养不良风险在老年瘤学实践中的临床意义.
- 调查营养不良风险与各种老年综合征和老年癌症患者死亡率之间的关联.
主要方法:
- 这项研究包括180名65岁及以上的癌症患者.
- 患者被评估为老年综合征,包括多药性,虚弱,可能的肉类,跌倒风险,动脉,抑郁症,认知障碍,失眠和过度的白天嗜睡.
- 营养不良风险是使用17-23.5之间的迷你营养评估得分来定义的,而得分>23.5表明营养状况良好.
主要成果:
- 在180名参与者中,营养不良风险的患病率为28.9%.
- 营养不良的风险与多药,小腿周长减少,跌倒风险,抑郁,失眠和虚弱有显著关联.
- 与营养良好患者相比,患有营养不良风险的患者的平均存活时间明显较短 (21.3个月) (平均存活时间未达到).
结论:
- 营养不良风险是老年癌症患者全因死亡率的重要预测因素.
- 该研究强调了营养不良风险与多重老年综合征之间的关联,强调了其在老年瘤学实践中的临床重要性.
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