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血清尿酸,高尿血和牙周炎之间的关联:使用NHANES数据进行的横截面研究

Jing Xu¹, Yifan Jia¹, Zhi Mao¹

¹Hospital of Stomatology, Jilin University, Changchun, Jilin Province, 130000, China.

BMC oral health

|August 29, 2023

概括

血清尿酸 (SUA) 水平与牙周炎风险有复杂的关系. 在女性中,较高的SUA与风险增加有关,而在男性中,在某些范围内,较高的SUA似乎具有保护作用.

科学领域:

代谢性疾病研究研究.
牙周病学牙周病学
发现生物标志物的发现.

背景情况:

像糖尿病这样的代谢疾病与牙周炎有关.
血清尿酸 (SUA) 和高尿血症在牙周炎中的作用仍未得到充分研究.

研究的目的:

为了研究血清尿酸 (SUA) 水平,高尿血和牙周炎之间的关系.
在男性和女性中分别分析这些关联.

主要方法:

利用了2011-2014年国家健康和营养检查调查 (NHANES) 的数据.
采用多变量逻辑回归模型来评估关联.
基于男性和女性SUA水平的牙周炎的计算几率比率 (OR).

主要成果:

在女性中,SUA水平为4.1-4.3 mg/dL与牙周炎的几率增加有关 (OR=1.43).
在男性中,SUA水平升高 (例如,4.9-6.5 mg/dL) 与牙周炎的几率降低有关 (ORs从0.58到0.67).
在男性中,这种关联显示出在特定范围内具有保护作用,其次是非显著的增加.

结论:

血清尿酸水平显示出与牙周炎风险的性别特异关联.
需要进一步的研究来证实SUA作为牙周炎的诊断生物标志物或治疗点的作用和潜力.

关键词:

超性血症 (hyperuricemia) 是一种疾病,口腔健康口腔健康牙周病是牙周病的一种疾病.牙周健康牙周健康尿酸是什么尿酸是什么

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