COVID-19感染对胃肠道的影响,考虑在内镜手术期间的预防方法
Sakiko Naito1, Itaru Nakamura2, Tomohiro Umezu3
1Department of Gastroenterology and Hepatology Tokyo Medical University Tokyo Japan.
DEN open
|August 30, 2023
概括
严重急性呼吸道综合征冠状病毒2 (SARS-CoV-2) 可以感染胃肠道,在内镜手术期间构成感染风险. 老年患者和患有恶性瘤的人面临更高的风险,需要加强保护措施.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 已知严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 影响呼吸系统.
- 新出现的证据表明2019年新冠肺炎 (COVID-19) 患者的胃肠道 (GI) 参与.
- 在内镜手术期间的环境污染是感染传播的担忧.
研究的目的:
- 为了调查COVID-19患者的便样本中SARS-CoV-2的存在和风险因素.
- 在内镜手术期间评估SARS-CoV-2的便-口腔传播潜力.
- 为开发内镜感染预防策略提供信息.
主要方法:
- 在一个单一的中心进行了前性观察研究.
- 来自32名COVID-19患者的便样本使用逆转录酶-聚合酶链反应 (RT-PCR) 进行了SARS-CoV-2检测.
- 风险因素包括年龄,并发症 (恶性瘤),疫苗接种状态和症状在便阳性方面进行了分析.
主要成果:
- 在测试患者中,便SARS-CoV-2阳性率为21.8%.
- 在65岁以上的患者 (71.4%),患有恶性瘤的患者 (71.4%),在BA.5变种爆发期间 (100%) 和有腹症状的患者 (42.9%) 观察到较高的阳性率.
- 便样本在初始采样后2天内呈阳性.
结论:
- 在感染者的便中可以检测到SARS-CoV-2,这表明存在潜在的胃肠道感染和便-口腔传播风险.
- 老年患者,患有恶性瘤的免疫功能低下个体以及患有腹的人面临更高的风险.
- 强化个人防护设备,包括眼睛保护,建议在内镜手术期间,以减轻感染风险.
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