在正常和脱落条件下对膜的比较建模
Seyed Esmail Razavi1, Amin Talebi1
1Faculty of Mechanical Engineering, University of Tabriz, Tabriz, Iran.
BioImpacts : BI
|August 30, 2023
概括
mitra valve prolapse (MVP) 的计算建模揭示了增加的压力和反的严重程度. 这些模拟为治疗MVP和理解中枢动力学提供了洞察力.
科学领域:
- 生物医学工程 生物医学工程
- 心血管研究研究心血管研究
- 计算流体动力学的流体动力学.
背景情况:
- mitra valve prolapse (MVP) 是最常见的膜疾病,通常是由 chordae tendineae 破裂引起的,导致 mitra valve regurgitation (MR).
- 非侵入性计算建模为了解健康和疾病状态中的二手 (MV) 功能提供了强大的工具.
研究的目的:
- 开发和利用基于图像的流体结构相互作用 (FSI) 模型来模拟人类的MV功能.
- 为了比较一个健康的MV的生物力学和血液动力学行为与一个呈现后部叶片落的MV.
主要方法:
- 从计算机断层扫描成像数据创建了详细的3D MV几何.
- 模拟了使用流体结构相互作用 (FSI) 模型与任意拉格朗-欧勒尔有限元素方法模拟的正常和前进的MV条件.
- 对嵌入在血液体积中的模型应用了生理系统压力负载.
主要成果:
- 失落模型显示不完整的叶片合和显著更高的 mitrale 吐 (MR) 严重程度.
- 与正常门相比,在发的MV的后侧小册子中观察到压力增加.
- 涌喷气显示出较大的偏差向左心房壁在形条件下.
结论:
- 计算模型准确地预测了MVP中增加的MR严重程度和传单压力.
- 这些发现有助于更好地了解MV在的动态,帮助临床治疗策略.
- 模拟为外科医生提供了对健康和疾病期间的MV行为有价值的见解.
相关概念视频
01:27Mitral Valve Prolapse I: Introduction
21
IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
21
01:22Mitral Valve Prolapse II: Assessment and Management
21
IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
21
01:20Mitral Regurgitation I: Introduction
16
Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
16
01:19Mitral Valve Prolapse III: Nursing Management
16
The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
16
01:23Mitral Regurgitation II: Clinical Features and Diagnostic Tests
22
Mitral regurgitation (MR) is a valvular heart disorder in which the mitral valve fails to close tightly, allowing blood to leak backward into the heart. Understanding the clinical manifestations, assessment, diagnostic findings, and medical management of MR is crucial to effectively managing affected patients.Clinical Manifestations of Mitral RegurgitationMitral regurgitation can be acute or chronic, each presenting differently and requiring different approaches:1. Acute Mitral...
22
01:23Mitral Stenosis II: Clinical features and Diagnostic Tests
22
Mitral stenosis is a heart condition in which the mitral valve, which allows blood to flow from the left atrium to the left ventricle, becomes narrowed or stenotic. This narrowing hinders blood flow and leads to clinical symptoms requiring specific medical evaluations and management strategies. The following overview outlines the clinical symptoms, assessments, diagnostic findings, prevention methods, and treatments for mitral stenosis.Clinical ManifestationsDyspnea (shortness of breath): This...
22