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肠道模型的翻译路线图,专注于肠上芯片

Giulia Malaguarnera1, Miriam Graute1, Antoni Homs Corbera1

  • 1R&D department, Cherry Biotech SAS, Rennes, Brittany, 35000, France.

Open research Europe
|August 30, 2023
PubMed
概括

在实验室中对人体肠道进行建模是具有挑战性的,原因是复杂的生物相互作用. 这份路线图指导研究人员在为临床前和转化研究选择肠上芯片模型.

关键词:
在芯片上的结肠.在芯片上的肠道.在芯片上的肠道.芯片上的微生物群器官在芯片上的器官肠道模型 肠道模型微流体中的微流体.

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Anatomy of the Intestines01:23

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Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
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The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the small...