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根据光信息对多种染色体进行光声学歧视,通过终身映射光学封闭的响应

Md S Islam¹, Donald VanderLaan², Josie Hickman¹

¹School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.

|August 30, 2023

概括

同步放大光声图像恢复 (SAPhIRe) 使用独特的对比剂寿命来区分信号. 这种技术成功地将孟加拉和酸Y信号不混合,使其能够在光声成像中同时检测.

科学领域:

生物医学光学生物医学光学
摄影声学成像技术的成像
对比剂开发对比剂开发

背景情况:

光声成像 (PAI) 提供高分辨率和深层组织透.
在同一光谱窗口内区分多种对比剂仍然是一个挑战.
具有独特的非线性性质的可调节对比剂可以提高PAI的特异性.

研究的目的:

为了证明同步放大光声图像恢复 (SAPhIRe) 的能力,以分离来自多种对比剂的信号.
为了验证使用三重状态生命周期映射用于独立信号检测.
在幻影中重建不同对比剂的不同图像.

主要方法:

使用了SAPhIRe,利用对比剂的非线性光学特性.
通过不同的探头延迟采用三重状态寿命映射.
使用光用于预成像调制查.
在模仿组织幻影中的三重状态生命周期的适配系数的重建图像.

主要成果:

根据它们独特的三重状态生命周期,成功地将孟加拉和eosin Y溶液中的未混合信号结合起来.
实现了快速衰变 (孟加拉) 和缓慢衰变 (欧Y) 的调制光声信号的分辨率和恢复.
在幻影中重建了两个对比剂的截然不同的图像.
证明光选有效地识别了PAI之前的调制.

结论:

SAPhIRe 能够独立检测具有重叠光谱的多种对比剂.
三重状态生命周期映射是一种可行的方法,用于在PAI中进行信号脱.
这种技术具有使用PAI同时检测多种病理的潜力.

关键词:

光是一种光效应.图像成像是一种成像.终身使用时间终身使用时间调制调制是一种调制.在OADF的OADF.摄影声学摄影声学三重状态的三重状态

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