帕金森病的轻微幻觉可能伴有眼睛快速运动睡眠行为障碍
Yinyin Jiang1, Jun Zhu1, Yang Zhao1
1Department of Geriatric Neurology, Nanjing Brain Hospital Affiliated to Nanjing Medical University, Nanjing, China.
Frontiers in neuroscience
|August 30, 2023
概括
帕金森病患者可能患有快速眼动睡眠行为障碍 (RBD),经常经历小幻觉 (MHs). 这些幻觉与更长的疾病持续时间和更严重的非运动症状有关.
科学领域:
- 神经学 神经学
- 睡眠医学 睡眠医学
- 神经科学是一个神经科学.
背景情况:
- 帕金森病 (PD) 通常伴有非运动症状.
- 快速眼动睡眠行为障碍 (RBD) 和轻微幻觉 (MHs) 在PD患者中很常见.
- 在PD中,MHs和可能的RBD (pRBD) 之间的关系需要进一步调查.
研究的目的:
- 在帕金森病 (PD) 患者中调查轻微幻觉 (MHs) 和可能的快速眼动睡眠行为障碍 (pRBD) 之间的联系.
主要方法:
- 一项涉及291名PD患者的横截面研究.
- 在RBD查问卷中,pRBD被定义为6分或以上的得分.
- 收集的数据包括人口统计,临床评估和MH特征.
主要成果:
- 在PD患者中,有23.7%的患者患有PRBD.
- 50.7%的pRBD患者存在MH,明显高于没有pRBD的患者 (29.7%).
- 患有prbd和mhs的患者年龄较大,疾病持续时间较长,在非运动症状问卷和汉密尔顿焦虑量表上得分较高.
结论:
- 轻微的幻觉在帕金森病患者中非常普遍,可能有RBD.
- 患有RBD的PD中的MH主要与疾病持续时间和非运动性症状的严重程度有关.
- 这些发现突出了MHS和RBD在PD进展中的相互作用.
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