为暴露性研究创建个人:HEAP项目经验
Heather Coombs1, Tracy Wootton2, Joakim Dillner3
1Learning and Capacity Building, International Agency for Research on Cancer, Lyon, 69337, France.
Open research Europe
|August 30, 2023
概括
发展人格有助于理解复杂领域的暴露体. 这些用户资料有助于有效地向科学家和公众传达一些研究.
科学领域:
- 环境健康科学 环境健康科学
- 生物信息学是一种生物信息学.
- 计算生物学 计算生物学
背景情况:
- 暴露体,包括从受孕到死亡的所有环境暴露,是一个复杂和不断增长的科学领域.
- 研究exposome需要高质量的数据和软件,在清晰的定义和结构化的沟通方面面临挑战.
- 需要一个结构化的方法,以提高对科学和公众的理解和交流暴露研究.
研究的目的:
- 开发一个结构化的框架,以理解和沟通一些研究.
- 创建工具,以帮助定义和呈现复杂的概念的exposome.
- 在曝光组数据生成和利用的背景下,改进人机交互.
主要方法:
- 通过三个重点小组开发14个独特的个性.
- 进行14次半结构面试,以确定暴露组研究中的子主题.
- 利用代表真实人群的个体来建模一些数据生成器和用户.
主要成果:
- 成功创建了14个人物,代表了暴露组研究中的关键用户群.
- 焦点小组定义了广泛的研究主题,而采访导致了子主题的和.
- 在HEAP项目的背景下,人员被开发出来,充当数据生成者和用户的双重角色.
结论:
- 人体,在计算机科学中成功应用于人与计算机的互动,为暴露组研究提供了有价值的工具.
- 创建exposome-specific personas支持对这个复杂的科学领域的教育和宣传工作.
- 这种方法提高了exposome科学对不同受众的清晰度和可访问性.
相关概念视频
Data Collection by Experiments
24.3K
Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
An example of the experimental method is a public...
24.3K
Background and Environment Affect Phenotype
6.6K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
6.6K
Data Collection by Observations
12.1K
Data collection refers to a systematic way of obtaining, observing, measuring, and analyzing accurate information. Observational studies are one of the most widely used methods of data collection. It involves collecting data by observing the behavior and physical characteristics of a sample without making any modifications to the sample.
An astronomer viewing the motion and brightness of stars in the sky and recording the data is an example of observational data collection. A botanist recording...
An astronomer viewing the motion and brightness of stars in the sky and recording the data is an example of observational data collection. A botanist recording...
12.1K
Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
Observational Studies
8.7K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
8.7K
Stereotype Content Model
14.8K
The Stereotype Content Model (SCM) was first proposed by Susan Fiske and her colleagues (Fiske, Cuddy, Glick & Xu, 2002; see also Fiske, 2012 and Fiske, 2017). The SCM specifies that when someone encounters a new group, they will stereotype them based on two metrics: warmth—or that group’s perceived intent, and how likely they are to provide help or inflict harm—and competence—or their ability to carry out that objective. Depending on the warmth-competence...
14.8K


