由于Dolosigranulum pigrum引起的本源 mitra 膜感染性内心炎
Caitlin C Schanz1, Mark P Layden1, Daniel C DeSimone2
1Department of Pharmacy Services, Mayo Clinic, Rochester, United States.
IDCases
|August 30, 2023
概括
Dolosigranulum pigrum,很少具有致病性,导致本地 mitra 感染性内心炎. 患者在接受了塞夫特里亚克森治疗和门修复后恢复过来,除了对红红素外,显示出对抗生素的敏感性.
科学领域:
- 传染性疾病 传染性疾病
- 心脏病学 心脏病学
- 微生物学 微生物学
背景情况:
- Dolosigranulum pigrum是一种无氧的,格拉姆阳性,不经常被认为是一种病原体.
- 以前的病例报告表明,D. pigrum参与了各种感染,包括细菌病和肺炎.
- 原生膜感染性内心炎是一种严重的疾病,通常是由更常见的病原体引起的.
研究的目的:
- 报告第一个Dolosigranulum pigrum病例,该病例导致本地 mitra 感染性内心炎.
- 描述这种罕见感染的临床表现和治疗方法.
- 为了评估D. pigrum分离的抗生素敏感性概况.
主要方法:
- 病例介绍:一个患有先天性心肌感染性内心炎的患者.
- 鉴定Dolosigranulum pigrum作为致病原体.
- 对分离物的抗微生物敏感性测试 (MIC).
- 临床治疗过程包括静脉注射抗生素和手术干预.
主要成果:
- Dolosigranulum pigrum被成功地确定为负责本地 mitra 感染性内心炎的病原体.
- 隔离物显示出对β-乳酸盐,勒沃素和万科米的最低抑制度 (MIC) 是有利的.
- 红素是唯一一个经过测试的抗生素,该分离物对其表现出耐药性.
- 患者在6周的静脉注射塞夫和随后的门修复过程中取得了成功的临床结果.
结论:
- Dolosigranulum pigrum可能是原生 mitra 膜感染性内心炎的致病原体.
- 及时诊断和适当的抗生素治疗,如 ceftriaxone,对于成功的管理至关重要.
- 这一案例凸显了在传染性内心炎中考虑不太常见的病原体的重要性.
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