相关实验视频

Updated: Aug 17, 2026

Bone Conditioned Medium: Preparation and Bioassay

Bone Conditioned Medium: Preparation and Bioassay

Published on: July 8, 2015

在删除原始包装后,对两种类型的骨移植替代品的无菌性和生物活性评估

Mehdi Ekhlasmand Kermani¹, Aida Kheiri², Reza Amid^2,3

¹Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.

Journal of advanced periodontology & implant dentistry

|August 30, 2023

概括

拆卸和重新封装骨移植 (异种移植和异种移植) 并没有影响其无菌性或生物活性. 这些发现表明,谨慎处理可以在手术过程中保持骨替代品的完整性.

科学领域:

生物材料科学生物材料科学
整形外科手术整形外科手术
微生物学微生物学

背景情况:

异种移植和异种移植的骨替代品对于骨缺陷的修复至关重要.
骨移植的灭菌可能会受到包装拆除的影响.

研究的目的:

评估开封和重新开封对全移植和异移植骨替代物的无菌性和生物活性的影响.
为了评估潜在的微生物污染和暴露于手术室空气后生物活性的变化.

主要方法:

商用全移植和异种移植小瓶经过三次重复的模拟手术室空气暴露,持续时间各不相同 (1秒至1小时).
使用微生物学测试和扫描电子显微镜 (SEM) 与能量散射X射线分析 (EDX) 来评估不育性和生物活性.

主要成果:

在拆装七天后,在任何骨移植样本中都没有检测到微生物生长.
在暴露后的全移植或异移植样本中没有观察到生物活性负面的变化.

结论:

该研究表明,在经过测试的条件下,开封和重新开封的程序不会损害骨移植的无菌性或生物活性.
建议进行进一步的研究,以探索其他有影响的因素,并且在骨移植过程中仍然应该遵循标准的消毒协议.

关键词:

整体移植是一种全移植.生物活性生物活性骨头移植骨头移植无菌性是一种无菌性.异种移植异种移植

更多相关视频

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Published on: March 29, 2018

Biological Compatibility Profile on Biomaterials for Bone Regeneration

Published on: November 16, 2018

相关概念视频

Cleaning, Sterilization, and Disinfection

Cleaning, Sterilization, and Disinfection

Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...