前脑α-synuclein小鼠模型中模板包含的形成是独立于LRRK2的

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Dylan J Dues1, Yue Ma1, An Phu Tran Nguyen1

  • 1Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan, USA.

bioRxiv : the preprint server for biology
|August 30, 2023
PubMed
概括

氨酸丰富的重复激酶2 (LRRK2) 在帕金森病模型中没有显著影响α-synuclein积累. 然而,LRRK2可能会影响与α-synuclein病理学相关的神经炎症.

关键词:
这是LRRK2莱维的身体.帕金森病是帕金森氏症的一种疾病.这是一种α-synuclein.动物模型动物模型微质细胞中的微质细胞神经退行症的神经退行症蛋白质聚合蛋白质的聚合物

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