便pH和氧化还原作为早产婴儿肠道微生物组的功能标志物
Jeffrey Letourneau1, LaShawndra Walker2, Se Hyang Han2
1Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27708.
bioRxiv : the preprint server for biology
|August 30, 2023
概括
便的pH和氧化还原潜力可以作为早产婴儿肠道健康的生物标志物. 这些测量,以及短链脂肪酸含量和微生物组合,可以帮助识别患有严重新生儿并发症风险的婴儿.
科学领域:
- 新生儿科学 新生儿科学
- 微生物学 微生物学
- 生物化学 生物化学
背景情况:
- 婴儿的肠道微生物组对于发育至关重要,但早产婴儿的改变与严重的并发症有关,如死肠炎和败血症.
- 目前的研究发现了微生物组合和疾病风险之间的联系,但缺乏用于早期风险识别的实际生物标志物.
- 了解肠道环境的代谢状态对于改善早产婴儿健康结果至关重要.
结论:
- 便的pH和氧化还原潜力显示出可能成为早产婴儿肠道代谢状态的生物标志物.
- 这些生理参数,以及微生物组分析,可能有助于识别患新生儿并发症风险的婴儿.
- 进一步的研究可以验证pH和氧化还原作为监测早产婴儿肠道健康的临床工具.
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