性别特异性影响儿童暴露于多种环境空气污染物如何影响青春期早期白质微观结构的发展
Megan Herting1, Devyn Cotter1, Hedyeh Ahmadi1
1University of Southern California.
Research square
|August 30, 2023
概括
细颗粒物 (PM2.5),二氧化 (NO2) 和臭氧 (O3) 的空气污染影响青少年大脑白质的发育. 观察到性别特异性影响,即使在低暴露水平下也可能产生长期后果.
科学领域:
- 神经科学是一个神经科学.
- 环境健康 环境健康
- 发展生物学 发展生物学
背景情况:
- 青少年大脑发育涉及显著的白质 (WM) 微观结构变化.
- 环境空气污染对大脑发育的影响,特别是在青春期,需要进一步调查.
- 基于性别的WM完整性的差异在年轻人中显著.
结论:
- 在青春期暴露于常见的空气污染物,如PM2.5,NO2和O3,可以改变白质的发育轨迹.
- 这些效应甚至在低于当前美国标准的度下也被观察到,突出显示了潜在的长期神经发育风险.
- 调查结果强调了性别分层分析对于了解空气污染对青少年的神经毒性影响的重要性.
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