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结合PI3K和MAPK抑制作用的协同作用抑制了PDAC

Bailey A Bye, Jarrid Jack, Alexandra Pierce

    bioRxiv : the preprint server for biology
    |August 30, 2023
    PubMed
    概括

    用Omipalisib和Trametinib针对MAPK和PI3K-AKT通路显著改善了胰腺癌模型中的生存率. 这种双重治疗策略为胰腺管道腺癌 (PDAC) 治疗提供了一个有希望的方法.

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