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Updated: Jul 17, 2025

Unraveling the Role of Discrete Areas of the Rat Brain in the Regulation of Ovulation through Reversible Inactivation by Tetrodotoxin Microinjections
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Published on: September 3, 2020

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在卵巢和下丘脑中,Srd5a1在青春期前发育过程中受到不同的调节和甲基化

Ben Bar-Sadeh1, Lilach Pnueli1, Sarai Keestra1,2

  • 1Faculty of Biology, Technion-Israel Institute of Technology, Haifa 32000, Israel.

Journal of the Endocrine Society
|August 30, 2023
PubMed
概括

这项研究表明,雌激醇 (E2) 通过甲基化敏感增强剂控制卵巢Srd5a1基因表达,影响生殖发育. 相比之下,在下丘脑中Srd5a1的表达是由葡萄糖皮质体调节的,而不是E2或甲基化.

关键词:
5α降解酶-1的使用.这是Srd5a1a1这是表观遗传学.在下丘脑中,下丘脑甲基化处理 甲基化处理卵巢 卵巢是一个卵巢.

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