相关实验视频

Updated: Jul 17, 2025

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

21.9K

RSK酸化的逐步和数字模式决定了胸膜选择的结果

Shintaro Funasaki1,2, Atsushi Hatano3, Hirokazu Nakatsumi1

  • 1Department of Molecular and Cellular Biology, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Fukuoka 812-8582, Japan.

iScience
|August 30, 2023
PubMed
概括

发育中的T细胞使用p90核糖体蛋白激酶 (RSK) 信号来区分高和低亲和度联结体,在小细胞选择过程中指导细胞命运. 这种RSK通路控制着亡,确保T细胞受体 (TCR) 功能正常.

关键词:
细胞生物学 细胞生物学免疫学 免疫学 免疫学

更多相关视频

Preparation and Applications of Organotypic Thymic Slice Cultures10:10

Preparation and Applications of Organotypic Thymic Slice Cultures

Published on: August 6, 2016

8.3K
Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms09:41

Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms

Published on: July 26, 2024

839

相关概念视频

Receptor Tyrosine Kinases01:26

Receptor Tyrosine Kinases

Receptor tyrosine kinases or RTKs are membrane-bound receptors that phosphorylate specific tyrosine on protein substrates. RTKs regulate cellular growth, differentiation, survival, and migration. They contain an extracellular ligand binding domain, a transmembrane domain, and a cytosolic tail with intrinsic kinase activity. Several extracellular signaling molecules activate RTKs in one or more ways and relay the signal downstream. Ligands such as platelet-derived growth factor (PDGF) or...
13.1K