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Updated: Jul 17, 2025

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
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Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

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对用于化物标签方案的生物正方形适用的四素-Cy3探针的评估

Evelin Albitz1,2, Krisztina Németh1, Gergely Knorr1

  • 1Chemical Biology Research Group, Institute of Organic Chemistry, Research Centre for Natural Sciences, Magyar tudósok krt. 2, H-1117, Budapest, Hungary. kele.peter@ttk.hu.

Organic & biomolecular chemistry
|August 30, 2023
PubMed
概括

研究人员开发了新的四素-Cy3探针,用于生物对等化学. 这些探测器通过内部转换火表现出增强的化性,提高了活细胞蛋白质标记效率.

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相关概念视频

Labeling DNA Probes03:31

Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...
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