肌肉形态和结构的中部胃膜在典型的发展儿童之间的不同祖先背景的肌肉形态和结构
Fenna Walhain1,2, Marlies Declerck3, Ruby Chin A Fat3
1Department of Anatomy, Anton de Kom University of Suriname, Paramaribo, Suriname.
Journal of anatomy
|August 30, 2023
概括
这项研究揭示了非洲,南亚和东南亚血统的典型发育儿童中中部胃肌长度,囊长度和笔角的显著差异. 特定于祖先的数据对于了解性脑 (SCP) 等疾病的肌肉形态至关重要.
科学领域:
- 儿科肌肉骨健康 儿科肌肉骨健康
- 比较解剖学的比较解剖学
- 生物医学工程 生物医学工程
背景情况:
- 肌肉超声波对于评估儿童的肌肉骨功能障碍至关重要,特别是患有性脑 (SCP) 的儿童.
- 关于肌肉形态和结构的现有研究主要涉及高加索人群,限制了对祖先变异的理解.
- 儿童在不同祖先背景的肌肉形态上的差异仍然未被充分探索.
研究的目的:
- 为了比较肌肉形态和结构的中部胃膜在典型的发展儿童来自非洲 (Maroon),南亚 (印度斯坦),和东南亚 (爪) 祖先在苏里南姆.
- 为未来的临床应用建立不同祖先群体肌肉参数的基线数据.
主要方法:
- 一项探索性队列研究包括100名典型发育的5-10岁儿童,来自马龙,印度斯坦和爪人的祖先.
- 使用3D自由手超声波测量中部胃的参数:肌肉肌单位 (MTU) 长度,肌肉腹部长度,肌长度,肌肉体积,肌肉厚度,解剖截面面积 (ACSA),带长度,笔纹角和生理截面面积 (PCSA).
- 统计分析涉及单向ANOVA与后期t测试,与年龄相匹配的每个祖先的25个孩子的组 (共75个).
主要成果:
- 在祖先群体之间的MTU长度,肌肉腹部长度,ACSA,PCSA和肌肉体积方面没有发现显著差异.
- 观察到肌长度,带长度和角的显著差异.
- 马龙儿童的肌较长,角较大,而马龙和印度斯坦儿童的带长度较短,而爪儿童的带长度较短.
结论:
- 这项研究是第一个研究宏观的中部胃膜体形态和结构在一个多样化的队列的典型发育儿童分层的祖先.
- 肌长度,囊长度和角的祖先特定参考数据对于准确评估儿科神经和神经肌肉疾病中的肌肉形态至关重要.
- 未来的研究应该将祖先的背景纳入和报告在儿科肌肉形态学的研究中,并将这些数据纳入规范数据库.
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