由EUS指导的胃肠静脉切除术:一项多中心国际研究,比较良性和恶性疾病
Michel Kahaleh1, Amy Tyberg1, Sohini Sameera1
1Department of Gastroenterology, Robert Wood Johnson University Hospital, New Brunswick, NJ.
Journal of clinical gastroenterology
|August 30, 2023
概括
以内镜超声波 (EUS) 引导的胃肠静脉切除术 (EUS-GE) 对良性和恶性胃出口阻塞的效率和不良事件相似. 这种微侵袭性疗法提供了一个可行的替代方案,无论潜在的疾病病因.
科学领域:
- 胃肠病学 胃肠病学
- 最少侵入性手术的方法
- 内镜超声波检查结果
背景情况:
- 以内镜超声波 (EUS) 引导的胃肠静脉切除术 (EUS-GE) 是胃出口阻塞的最小侵入性选择.
- 它避免了外科绕道风险和肠道支架的局限性.
- 基于潜在疾病病因学的EUS-GE结果存在有限的数据.
研究的目的:
- 为了比较EUS-GE在患有良性和恶性迹象的患者的长期结果.
- 评估不良事件,技术成功率和临床成功率.
主要方法:
- 在3年时间内,从12个国际中心连续12名患者的回顾性注册表分析.
- 收集的数据包括人口统计数据,程序细节和后续信息.
- 主要结果:不良事件发生率;次要结果:技术/临床成功,住院.
主要成果:
- 包括103名患者:72名恶性,31名良性.
- 对于两组患者来说,EUS-GE表现出类似的临床成功,技术成功,手术时间和住院时间.
- 患有良性病因的患者有更高的手术改变中肠解剖的发病率 (P=0.0379).
结论:
- 无论原因是良性还是恶性,EUS-GE是胃出口阻塞的有效治疗方法.
- 良性和恶性指示之间的不良事件率是可比的.
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