相关实验视频

Updated: Jul 17, 2025

Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education

Author Spotlight: Validation of SICOLE-R for Assessing Cognitive and Reading Skills in Spanish-Speaking Children and Its Role in Personalized Education

Published on: August 16, 2024

尿中2-基乙烯酸和学龄儿童的阅读障碍之间的关联

Haoxue Wang¹, Yanjian Wan², Qi Liu¹

¹Department of Maternal and Child Health and MOE (Ministry of Education) Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Wuhan, 430030, Hubei, China.

Environmental science and pollution research international

|August 30, 2023

概括

患有阅读障碍的儿童显示,与乙烯氧化物暴露相关的代谢物水平较高. 这表明,乙烯氧化物暴露与在学龄儿童中患阅读障碍的风险之间存在潜在的联系.

科学领域:

环境健康环境健康
神经发育障碍神经发育障碍
毒理学毒理学毒理学

背景情况:

乙烯氧化物 (EtO) 是一种已知的致癌性和神经毒性工业化学物质.
暴露于EtO与神经发育障碍 (如阅读障碍) 之间的联系尚未得到充分证实.
尿中的二乙烯酸 (HEMA) 是EtO暴露的生物标志物.

研究的目的:

调查尿液HEMA度与儿童阅读障碍风险之间的关联.
评估中国学龄儿童中EtO暴露的发生率.

主要方法:

一项涉及355名阅读障碍儿童和来自中国三个城市的390名对照儿童的病例对照研究.
用经过验证的分析方法测量尿液中的HEMA水平.
使用统计分析,包括多变量调整模型,来评估相关性.

主要成果:

在所有参与者中检测到尿液HEMA,表明广泛的EtO暴露.
患有阅读障碍的儿童的尿液HEMA度明显高于对照组 (几何平均值:2.92与2.47 ng/mL).
较高的HEMA水平与阅读障碍的几率增加有关,最高四分位数显示风险增加1.97倍.

结论:

尿液中的HEMA度与学龄儿童的阅读障碍风险增加有显著的关联.
这些发现表明,乙烯氧化物暴露在阅读障碍病因学的潜在作用.
需要进一步的研究来证实这些结果,并阐明底层的生物机制.

关键词:

2-基乙烯二甲酸是什么? 2-基乙烯二甲酸是什么生物监测生物监测阅读障碍症阅读障碍症是指阅读障碍.乙烯氧化物乙烯氧化物神经发育障碍神经发育障碍学校年龄的孩子们.

更多相关视频

Assessing Dyslexia at Six Year of Age

Assessing Dyslexia at Six Year of Age

Published on: May 1, 2020

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

相关概念视频

Learning Disabilities

Learning Disabilities

Learning disabilities are cognitive disorders caused by neurological impairments that affect cognitive functions like language and reading, without indicating overall intellectual or developmental challenges. These disabilities differ from global intellectual or developmental disabilities as they are limited to distinct cognitive functions. Common learning disabilities include dysgraphia, dyslexia, and dyscalculia, each of which impacts unique aspects of learning.
Dyslexia
Dyslexia is a...

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Language and Cognition

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.

Urine Studies I: Urinalysis

Urine Studies I: Urinalysis

Urinalysis is a widely used diagnostic test that analyzes urine's physical, chemical, and microscopic characteristics. Healthcare providers use it to detect and monitor various health conditions, including renal disease, urinary tract infections (UTIs), diabetes, and metabolic or systemic disorders.Components of UrinalysisUrinalysis consists of three primary components: physical, chemical, and microscopic examination. Each provides unique insights into the urine sample and, by extension, the...