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Updated: Jul 17, 2025

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骨髓细胞的TREM1激活促进了抗瘤免疫力

Vladislava Juric1, Erin Mayes1, Mikhail Binnewies1

  • 1Pionyr Immunotherapeutics, 2 Tower Place, Suite 800, South San Francisco, CA 94080, USA.

Science translational medicine
|August 30, 2023
PubMed
概括

阻断PY159在髓状细胞-1 (TREM1) 上表达的触发受体可以增强抗瘤免疫力. 这种新的免疫疗法策略通过激活髓状细胞来促进促炎性瘤微环境 (TME),为癌症治疗提供了一种有前途的方法.

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