在精神分裂症患者中,西对无情的作用
Alen Greš1, Marina Šagud1, Aleksandra Dickov2
1Department of Psychiatry and Psychological Medicine, University Hospital Center Zagreb, Zagreb, Croatia.
International journal of psychiatry in medicine
|August 30, 2023
概括
在精神分裂症患者中,Vortioxetine有效地减少了社会和身体上的无情感. 结合西和奥兰扎,显示出改善这些症状的最佳结果.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 无情是精神分裂症和抑郁症的一个关键症状.
- 了解精神分裂症中无症的治疗方法至关重要.
研究的目的:
- 为了研究vortioxetine在治疗精神分裂症患者无意识症的疗效.
- 评估沃尔提奥塞丁对社会和身体无情感的影响.
主要方法:
- 120名精神分裂症患者在缓解过程中被随机分配到伏尔托西干预组或对照组.
- 参与者接受了西 (10毫克/天) 或安慰剂,以及现有的抗精神病药物 (奥兰扎宾,瑞斯佩里,阿里皮普拉).
- 评估包括12周的PANSS,CDSS和查普曼尺度.
主要成果:
- 沃尔提奥塞丁显著改善了身体无情感 (F = 3.17,P < .05).
- 伏尔提奥塞丁对社会无情有强烈的积极影响 (F = 5.04,P < 0.01).
- 西与抗精神病类药物之间的相互作用是统计学上显著的.
结论:
- 沃尔提奥塞丁有效地减少精神分裂症的社会和身体无情感.
- 松平和西的组合似乎是最有利于管理无情症的症状.
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