tympanomastoidectomy与儿科耳鼻的亲肠道抗生素治疗相比
Eric Babajanian1, Christopher Nielson2, Chong Zhang3
1Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Utah School of Medicine, Salt Lake City, UT, United States of America.
American journal of otolaryngology
|August 30, 2023
概括
对于带有耳的儿科慢性支性耳中炎 (CSOM), tympanomastoidectomy显示症状的缓解速度比抗生素更快. 然而,经过对双边疾病等因素进行调整后,差异并不显著. 这两种治疗都具有相似的并发症率.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿童传染病 儿童传染病
- 手术疗效的研究
背景情况:
- 慢性性耳中炎 (CSOM) 与耳是常见的儿科疾病.
- 管理通常涉及抗生素或外科干预,但对特定儿科群体进行比较的证据有限.
- 没有胆固醇瘤的CSOM儿童的耳需要有效的治疗策略.
研究的目的:
- 为了比较 tympanomastoidectomy 和亲肠道抗生素治疗对儿童患者的耳鼻治疗的疗效.
- 评估每种模式的耳鼻和与治疗相关的并发症的解决时间.
- 确定影响该患者群体治疗结果的因素.
主要方法:
- 对221名儿科患者 (0-18岁) 的回顾性评估,这些患者在三级学术儿科医院接受耳鼻治疗.
- 纳入标准包括先前的抗生素治疗, tympanostomy管史,耳鼻,以及使用 tympanomastoidectomy 或亲肠抗生素的治疗.
- 使用考克斯比例危险模型分析解决的时间,调整年龄,双耳疾病和并发症.
主要成果:
- 58名儿童的83只耳朵符合纳入标准.
- tympanomastoidectomy最初显示了较短的中位时间来解决 (9个月) 与亲肠道抗生素 (48.5个月) 相比 (p=0.006).
- 多变量分析显示,双耳耳病状况是与解决时间相关的唯一独立因素 (HR 0.4,p=0.03). 两种治疗方法之间没有观察到并发症发生率的显著差异 (p=0.37).
结论:
- 在调整了混杂因素后,在儿科CSOM患者的耳切除术和亲肠道抗生素治疗之间,耳切除的解决时间没有显著差异.
- 管理的决定应该包括对手术和抗生素方法的风险和益处的彻底讨论.
- 在预测这群人中耳治疗结果时,双边耳病状态是重要的考虑因素.
关键词:
慢性耳部疾病 慢性耳部疾病慢性中耳炎 中耳炎.这就是Otorrhea的原因.亲肠道抗生素的使用.儿科 儿科 儿科儿科耳鼻病 儿科耳鼻病tympanomastoidectomy 这是一种小膜切除术.更多相关视频
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