在患有重度抑郁症的青少年中,自动正负情绪调节
Wenhai Zhang1,2, Cancan Zhao3,4, Fanggui Tang2
1Mental Health Center, Yancheng Institute of Technology, Yancheng, China.
Psychopathology
|August 30, 2023
概括
患有严重抑郁症的青少年表现出自动情绪调节受损,对积极刺激的注意力缺陷和对负面刺激的反应抑制.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 发展心理学 发展心理学
背景情况:
- 患有严重抑郁症 (MDD) 的青少年对情绪刺激表现出神经反应的改变.
- 自动情绪调节 (AER) 涉及关键的大脑网络,包括中央控制,默认模式和突出网络.
研究的目的:
- 研究患有多重抑郁症的青少年AER的时空缺陷.
- 为了比较MDD和没有MDD的青少年在积极和消极情绪刺激期间的AER.
主要方法:
- 电脑电图 (EEG) 数据是在情绪化的Go/NoGo任务期间从患有MDD的青少年和健康对照组中收集的.
- 在AER期间的皮质活动动态被分析为时空特征.
主要成果:
- 患有MDD的青少年在Go试验中显示了N2幅度的降低和对积极刺激的提达功率的增强.
- 在NoGo试验中,MDD青少年表现出高的P3幅度和前额和岛屿区域之间的信息流模式的改变.
结论:
- 患有MDD的青少年表现出对积极情绪的自动注意力受损,对负面刺激的反应抑制.
- 这些发现表明青少年中MDD的潜在治疗点.
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