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Updated: Jul 17, 2025

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
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在雌激素受体上酸262的突变取消了雌激醇信号通路

Xingyan Xu1,2, Haowei Yu1,2, Shuihao Zhu1,2

  • 1Department of Basic Medical Research, Sixth Affiliated Hospital of Guangzhou Medical University, Qingyuan People's Hospital, Key Laboratory of Cardiovascular Diseases, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, P.R. China.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
|August 30, 2023
PubMed
概括

雌激素受体α (ERα) 中的酸262对于基因组和非基因组雌激素效应至关重要. 这项研究生成了一个小鼠模型,显示子宫发育和血管功能受损,突出显示了ERα的双重作用.

关键词:
雌激素受体的受体是什么基因组行动 基因组行动非基因组影响血管的影响 血管影响

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