轻度认知障碍的新型液体生物标志物:系统性审查和元分析
Amish Gaur1, Luc Rivet1, Ethan Mah1
1Hurvitz Brain Sciences Program, Sunnybrook Research Institute, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada; Department of Pharmacology & Toxicology, University of Toronto, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.
Ageing research reviews
|August 30, 2023
概括
像神经纤维光链 (NfL) 和状纤维酸蛋白 (GFAP) 这样的液体生物标志物在轻度认知障碍 (MCI) 中升高. 在血液或脑液中监测这些可能会揭示MCI患者的神经退行.
科学领域:
- 神经科学是一个神经科学.
- 生物标志物研究 生物标志物研究
背景情况:
- 轻度认知障碍 (MCI) 是痴呆症的前体,经常显示早期的神经退行.
- 确定可靠的液体生物标志物对于描述MCI病理生理学至关重要.
结论:
- 液体生物标志物,特别是NfL和GFAP,在检测MCI中神经退行方面表现有前途.
- 在临床环境中监测这些生物标志物可以提供有关MCI潜在病理过程的见解.
更多相关视频
07:30Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
3.1K
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
32.4K
相关概念视频
Alzheimer's Disease: Overview
517
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
517
Cognitive Development During Adulthood
155
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
155
