在急性心肌梗塞之后的非心血管发病率和死亡率的时间趋势

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Daniel Mølager Christensen¹, Jarl Emanuel Strange², Mohamad El-Chouli³

¹Danish Heart Foundation, Copenhagen, Denmark.

Journal of the American College of Cardiology

|August 30, 2023

概括

改善的心肌梗塞 (MI) 护理允许生存,但癌症和感染等非心血管疾病正在增加. 非心血管病因现在占心脏病发作后死亡的比例较大,需要临床治疗.

科学领域:

心脏病学心脏病学
公共卫生公共卫生
流行病学流行病学

背景情况:

改善心肌梗塞 (MI) 的管理和护理已经导致患者的存活率增加.
长期存活下来的心肌梗塞患者越来越多地发展出严重的非心血管疾病.
这一趋势需要对MI后不断变化的健康格局进行调查.

研究的目的:

调查心肌梗塞 (MI) 后非心血管疾病发病率和死亡率的时间趋势.
评估癌症,脏疾病和传染病发病率的变化后MI.
为了确定非心血管病因在整体心脏病发作后死亡率中的变化比例.

主要方法:

一项全国性的队列研究,利用2000年至2017年的丹麦注册数据.
包括所有在研究期间被诊断患有心脏病的患者.
结果分析包括心血管和非心血管死亡率,发生癌症,脏疾病和传染病.

主要成果:

在2000-2002年至2015-2017年期间,观察到心血管病发后1年心血管死亡率显著下降 (18.4%至7.6%).
非心血管疾病死亡率有较小的下降 (5.8%至5.0%),导致非心血管疾病导致的总死亡率比例增加 (24.1%至39.5%).
发病癌症 (1.9%-2.4%),病 (1.0%-1.6%) 和传染病 (5.5%-9.1%) 的1年风险增加,在标准化后,病和传染病风险仍然较高.

结论:

尽管心血管结果有所改善,但心血管以外的发病率在心肌梗塞幸存者中正在上升.
非心血管疾病在心肌梗塞后的死亡率占比越来越高.
临床指导方针和未来的研究应该优先考虑心血管疾病以外的治疗结果.

关键词:

死亡率死亡率其他非心血管疾病.结果就是结果.登记处的注册表可以看到.趋势趋势趋势

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