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Updated: Jul 17, 2025

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具有已知的抗原特异性的T细胞受体的大规模基于模板的结构建模揭示了互补性特征

Dmitrii S Shcherbinin1,2, Vadim K Karnaukhov3, Ivan V Zvyagin4

  • 1Institute of Translational Medicine, Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Pirogov Russian National Research Medical University, Moscow, Russia.

Frontiers in immunology
|August 31, 2023
PubMed
概括

这项研究模拟了T细胞受体 (TCR) - -主要基因相容复合体 (MHC) 相互作用,以预测TCR特异性. 开发的方法产生各种抗原的高质量的TCR--MHC模型,有助于理解免疫反应.

关键词:
这种T细胞受体是T细胞受体.这是一个TCR--MHC复合体.抗原识别对抗原的识别我们的数据库数据库数据库数据库.结构建模结构建模

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