相关实验视频

Updated: Jul 17, 2025

Non-invasive Assessment of Microvascular and Endothelial Function

Non-invasive Assessment of Microvascular and Endothelial Function

Published on: January 29, 2013

间歇性与持续的手握运动和外围内皮功能:剪切速率波动的影响

Brady E Hanson¹, Darren P Casey^1,2,3

¹Department of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.

Journal of applied physiology (Bethesda, Md. : 1985)

|August 31, 2023

概括

在手握练习期间间歇性提高剪切率 (SR) 可能比持续的提升更有效地改善内皮功能. 这项研究发现,间歇性炼比持续性炼更能急剧增强外围内皮功能.

科学领域:

生理学生理学生理学
心血管健康心血管健康
运动科学运动科学

背景情况:

已知持续的运动诱导的剪切速率 (SR) 升高有利于内皮功能.
间歇性SR波动对外围内皮功能的影响尚不清楚.

研究的目的:

为了比较间歇性与持续性SR升高对外周内皮功能的影响.
为了研究不同运动方案对手臂动脉流媒扩张 (FMD) 的急性影响.

主要方法:

13名健康成年人进行了三个30分钟的手握运动方案:间歇性在25%的MVC (INT-25%),间歇性在15%的MVC (INT-15%) 和连续性在15%的MVC.
用多普勒超声波测量手臂动脉直径和速度,以评估SR和FMD.
在每次运动干预之前和之后评估了口病.

主要成果:

所有的炼方案都增加了口炎,但在INT-25%和INT-15%和持续炼相比,这种增加明显更大.
曲线下的正常化口病与剪切率面积在间歇性炼 (INT-25%和INT-15%) 时显著增加,但在持续炼时没有显著增加.
与连续升高相比,间歇性SR升高产生了较大的内皮功能急性改善,尽管总SR增加类似.

结论:

在手握运动期间,剪速的间歇性波动可能比持续的升高更有效地刺激了外围内皮功能急性改善.
新发现表明间歇性炼方案可能是增强内皮功能的一种优越策略.

关键词:

间歇性运动是间歇性的运动.周围的内皮功能.剪切率是指剪切速度的速度.

更多相关视频

The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress

The Assembly and Application of 'Shear Rings': A Novel Endothelial Model for Orbital, Unidirectional and Periodic Fluid Flow and Shear Stress

Published on: October 31, 2016

Human Saphenous Vein Endothelial Cell Isolation and Exposure to Controlled Levels of Shear Stress and Stretch

Human Saphenous Vein Endothelial Cell Isolation and Exposure to Controlled Levels of Shear Stress and Stretch

Published on: April 21, 2023

相关概念视频

Exercise and Cardiovascular Response

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...

Autoregulation of Blood Flow

Autoregulation of Blood Flow

Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation....