在异性造血细胞移植之前的牙科评估和清除
David Dean1, Stephanie J Lee2, Corey Cutler3
1University of Washington School of Dentistry, Seattle, Washington, USA.
Oral diseases
|August 31, 2023
概括
在全源造血干细胞移植 (Allo-HSCT) 之前进行牙科评估至关重要. 这项研究发现,在接受Allo-HSCT的患者中,牙科疾病负担较低,治疗机会很高.
科学领域:
- 血液学 血液学 血液学
- 在瘤学瘤学.
- 口腔健康 口腔健康
背景情况:
- 移植前的牙清洁对于全源造血干细胞移植 (Allo-HSCT) 至关重要,以减轻中性质衰竭期间的感染风险.
- 在这种患者群体中,牙科疾病和治疗需求的程度仍然不完全理解.
研究的目的:
- 描述接受Allo-HSCT的患者的牙状况和移植前治疗.
- 在两个主要的移植中心的大型队列中评估牙科发现和干预措施.
主要方法:
- 从两个移植中心 (弗雷德·哈森和达纳-法伯) 的486名患者的牙科数据进行了回顾性分析.
- 由校准的口腔健康专家从医疗记录中抽取数据.
- 包括有机构牙科清除计划的患者.
主要成果:
- 队列中位年龄为55.9岁,62.1%的男性和88%的白人患者.
- 移植前的牙科发现包括31.2%未经治疗的虫和91.6%的修复; 13.2%的牙被拔掉.
- 清除后,牙的平均数量略有下降,从26.0降至25.6.6.
结论:
- 在Allo-HSCT前的牙科评估显示,这个队列中牙科疾病的负担很低.
- 结果表明,人们获得牙科护理的机会很高,而且移植前的牙科干预也很成功.
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