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细胞外矩阵刚度通过控制内皮膜膜信号来调节微血管稳定,以确定细胞命运

Yali Yu1,2,3, Yu Leng1,2, Xiuyue Song1,2

  • 1Institute for Translational Medicine, The Affiliated Hospital of Qingdao University, Medical College, Qingdao University, China (Y.Y., Y. Leng, X.S., J.M., L.M., L.Y., Y.Z., J.L., D.W.).

Arteriosclerosis, thrombosis, and vascular biology
|August 31, 2023
PubMed
概括

细胞外矩阵 (ECM) 刚性和TGFβ信号合作调节微血管稳定性. 刚性ECM促进内皮细胞ITGB1酸化和CTGF分泌,诱导周细胞-肌纤维细胞分化和纤维化.

关键词:
细胞分化的细胞分化.内皮细胞是内皮细胞.纤维化 纤维化肌纤维母细胞细胞.周围细胞 (pericytes) 是一个细胞.

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