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Updated: Jul 17, 2025

Immunostaining for DNA Modifications: Computational Analysis of Confocal Images
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Published on: September 7, 2017

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通过新型转录因子结合模型揭示了DNA甲基化和内基因依赖的广泛影响

Jan Grau1, Florian Schmidt2,3,4,5, Marcel H Schulz2,3,6,7

  • 1Institute of Computer Science, Martin Luther University Halle-Wittenberg, Halle 06120, Germany.

Nucleic acids research
|August 31, 2023
PubMed
概括

DNA甲基化会影响转录因子 (TF) 的结合. 我们的新工具MeDeMo模拟了这一点,揭示了甲基化往往会降低TF结合,并突出了因子内依赖性对准确分析的重要性.

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