一项前性干预研究,以确定与药物相关的急诊室访问,比较标准护理组和药物护理组
Benjamin J Hellinger1,2,3, André Gries1, Susanne Schiek3,4
1Emergency Department/Surveillance Ward Leipzig University Hospital.
概括
将临床药剂师纳入急诊室显著改善了与药物相关的急诊室访问的识别. 这导致更多的干预措施,如停止因果药物治疗,以获得更好的患者结果.
科学领域:
- 药理学 药理学是指药理学的学科.
- 临床药房 临床药房
- 紧急医疗 紧急医疗
背景情况:
- 药物不良反应 (ADRs) 是一个很大的负担,经常导致住院治疗,在急诊室 (EDs) 经常被错误识别.
- 临床药剂师可以在识别ADR方面发挥关键作用,尽管他们融入ED团队并非常规.
研究的目的:
- 为了比较一个集成临床药剂师组与标准护理组的药物相关急诊室 (ED) 访问率.
- 评估临床药剂师干预对识别和管理与药物相关的ED表现的影响.
主要方法:
- 在德国莱比锡的第三级护理大学医院ED进行的一项前性干预研究.
- 50岁及以上的患者被纳入标准护理组 (2020年3月至5月) 或配合综合临床药剂师的制药组 (2021年3月至5月).
- 临床药剂师提供了详细的药物历史和分析,以支持ED团队评估访问的药物相关性.
主要成果:
- 与标准组相比,制药组发现了与药物相关的ED访问量 (12.6%) 显著增加 (3.9%),增加了三倍以上 (OR 3.56).
- 对患者药物治疗的干预,包括停药和剂量降低,在药物组中进行了77例,在标准组中进行了16例.
- 与药物相关的ED访问组中的患者年龄较大 (中位数为77-78岁),在两组研究中都服用了更多药物 (中位数为7-9种药物).
结论:
- 在ED环境中实施临床药剂师与识别与药物相关的ED访问的明显改善有关.
- 与标准护理相比,药剂师的参与导致药物停用率和致病药物的剂量减少率显著提高.
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