从患者的角度来看,从药物不良反应的过程中制定框架结构主题的开发
Jette A van Lint1,2, Marlieke Sonnenberg3, Harald E Vonkeman4,5
1Netherlands Pharmacovigilance Centre Lareb, Goudsbloemvallei 7, 5237 MH, 's-Hertogenbosch, The Netherlands. Jette.vanlint@radboudumc.nl.
Drug safety
|August 31, 2023
概括
患者描述药物不良反应 (ADR) 的详细方面,包括频率,持续时间和影响因素. 这一框架从患者的角度增强了对ADR的理解,改善了向患者提供的信息.
科学领域:
- 药物监督 药物监督 药物监督
- 患者报告的结果
- 定性研究是指质量研究.
背景情况:
- 有限的以患者为中心的信息存在于药物不良反应 (ADR) 的过程中.
- 了解患者对ADR的看法对于改善药物安全沟通至关重要.
研究的目的:
- 开发一个框架,从患者的角度来描述ADRs的过程.
- 确定患者报告的ADR体验中的共同主题.
主要方法:
- 从三个数据集中对患者报告的ADR数据进行定性主题分析.
- 诱导方法应用于3888个报告的副作用.
- 基于确定的主题,开发一个概念框架.
主要成果:
- 确定了描述ADR过程的六个主要主题:频率,持续时间,发生,强度,触发因素和改善因素.
- 患者提供了关于他们ADR体验的时间方面和影响因素的详细信息.
- 分析揭示了影响ADR进展的描述性主题和因素.
结论:
- 一个新的框架捕捉了患者描述的ADR过程和时间框架的细节.
- 确定的主题可以指导系统的数据收集,以获得更全面的患者ADR信息.
- 这项研究为加强患者对药物不良反应的教育提供了基础.
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