在Tribolium castaneum (Coleoptera: Tenebrionidae) 中,Enterococcus faecalis诱导的素敏感性的分子机制
Zhengyan Wang1, Haisheng Hu1, Zhenzhen Chang1
1School of Food and Strategic Reserves, Henan University of Technology, Zhengzhou 450001, China.
Journal of economic entomology
|August 31, 2023
概括
肠道细菌Enterococcus faecalis减少了暴露于氨酸的Tribolium castaneum中的生存和健康. 这种细菌破坏了宿主.
科学领域:
- 昆虫毒理学 昆虫毒理学
- 微生物生态学 微生物生态学
- 害虫管理 害虫管理 害虫管理
背景情况:
- 石对烟雾剂氨酸具有显著的耐药性.
- 肠道微生物群在昆虫抗农药性中的作用尚未完全理解.
- 菌 (Enterococcus faecalis) 是Tribolium castaneum中的一个肠道共生体.
研究的目的:
- 调查Enterococcus faecalis对Tribolium castaneum中氨酸耐药性的影响.
- 阐明这种相互作用的潜在机制,重点关注氧化还原和免疫反应.
主要方法:
- 成年Tribolium castaneum受到了Enterococcus faecalis注射和/或素暴露的挑战.
- 评估死亡率,女性生育能力,氧化应激标志物和免疫反应.
- 评估了抗氧化酶的表达和活性 (氧化物脱酶,酸酶,过氧化酶) 和免疫信号通路.
主要成果:
- 在暴露于素的Tribolium castaneum中,Enterococcus faecalis注射降低了生存率和女性生育能力.
- E. faecalis加剧了氧化应激,并抑制了宿主中的抗氧化酶活性.
- 过度的宿主免疫反应,包括免疫缺陷途径和双氧化酶反应性氧物种系统,被触发.
结论:
- Enterococcus faecalis通过干扰宿主的氧化还原系统来负面调节宿主的氨酸抵抗.
- 肠道共生生物可以显著影响昆虫的农药耐药性.
- 研究结果提供了有关昆虫微生物相互作用的见解,以及新的农药耐药性管理策略.
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