针对癌症患者药物坚持和临床结果的先进信息干预:随机对照试验
Chen-Xu Ni1, Wen-Jie Lu1, Min Ni1
1Department of Pharmacy, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
JMIR cancer
|August 31, 2023
概括
与第二代 (2G) 消息相比,第五代 (5G) 消息显著改善了癌症患者的药物坚持和临床结果. 这种5G干预增加了叶酸和维生素B12水平,并减少了白血病.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 临床药房 临床药房
背景情况:
- 药物坚持对于癌症治疗疗效和患者生活质量至关重要.
- 缺乏坚持性和不良药物反应可能会影响癌症治疗的结果.
- 通信技术的进步,如第五代 (5G) 消息传输,提供了新的干预可能性.
研究的目的:
- 评估5G消息对中国癌症患者药物坚持和临床结果的影响.
- 在试点随机对照试验中,将5G消息传递与传统第二代 (2G) 消息传递的有效性进行比较.
主要方法:
- 一项前性试点随机受控试验与接受米化疗的非小细胞肺癌患者进行.
- 患者接受叶酸和维生素B12补充剂,组分为5G或2G消息干预.
- 药物坚持,生活质量,化疗毒性和血清维生素水平在基线,1个月和3个月被评估.
主要成果:
- 与2G组相比,5G消息组在1个月 (90%对76%) 和3个月 (83%对75%) 的药物坚持率显著更高.
- 5G组患者的叶酸和维生素B12的血清水平较高.
- 5G组的白血病发病率 (16%) 比2G组 (31%) 低,其他毒性或生活质量没有显著差异.
结论:
- 与传统的2G消息相比,第五代 (5G) 消息传递是一种优越的干预措施,可以提高癌症患者的药物坚持.
- 5G干预积极影响关键的临床结果,包括改善维生素水平和减少化疗诱导的白血病.
- 这种技术驱动的方法有望优化癌症护理和患者管理.
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