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在Bordetella pertussis感染中依赖DNA的干扰素诱导和肺炎

Jeremy Ardanuy1, Karen M Scanlon1, Ciaran Skerry1

  • 1Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research
|August 31, 2023
PubMed
概括

Bordetella pertussis感染通过像TLR9和STING这样的DNA感知模式识别受体 (PRR) 触发肺炎,这些受体会诱导I/III型干扰素 (IFN). 这揭示了 pertussis 病原发生的关键机制.

关键词:
波多菌百日咳感染模式识别受体的模式识别受体这是一种I型干扰子.第三类干扰素干扰素.

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