对SARS-CoV-2脉冲载荷采样策略的分析:对基于废水的流行病学的影响
Albert Wilhelm König1, Sarah Sydney Ariano2, Darko Joksimovic3
1Institute of Urban Water Management and Landscape Water Engineering, Graz University of Technolog, Stremayrgasse 10/1, Graz 8010, Austria
概括
针对SARS-CoV-2 (COVID-19) 的废水采样最准确的是使用更频繁,更长的采样周期,而不是特定的权重方法. 避免抓取样本以获得可靠的废水流行病学结果.
科学领域:
- 环境科学环境科学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 基于废水的流行病学 (WBE) 是监测传染病如SARS-CoV-2 (COVID-19) 的一个有价值的工具.
- 优化废水采样策略对于准确估计大群体的流行率至关重要.
研究的目的:
- 评估不同废水采样活动设计对估计SARS-CoV-2流行率的影响.
- 确定基于废水的流行病学最有效的抽样策略.
主要方法:
- 应用了便运输模型和随机废水和水质模型.
- 模拟了加拿大多伦多11.3平方公里的11个不同的虚拟采样活动.
- 根据权重方法,样本数,采集期和干燥天气流动期间的样本时间进行评估的采样活动.
主要成果:
- 采样活动的样本数量较高,持续时间较长,产生了更可靠的SARS-CoV-2流行率估计.
- 选择权重方法 (时间,体积或流量) 对结果的影响微不足道.
- 建议避免抓取样本,以提高准确性.
结论:
- 增加采样频率和持续时间是提高基于废水的流行病学准确性的关键.
- 投资流量监测设备进行加权采样是不必要的增强WBE的结果.
- 标准基于时间的采样足以通过废水进行有效的SARS-CoV-2监测.
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