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备份转录因子结合部位保护人类基因免受促进因子突变的影响

Jay C Brown1

  • 1Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia, United States of America.

PloS one
|August 31, 2023
PubMed
概括

人类基因调节区域通过冗余的转录因子/结合位点对抵抗突变. 这些丰富的对确保了基因表达的稳定性,在大脑和肝脏组织中发现了特定的部位.

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