听觉皮层组合共同编码声音和运动速度,以支持运动期间的声音感知
Carlos Arturo Vivaldo1, Joonyeup Lee1, MaryClaire Shorkey1
1Department of Psychology, University of Michigan, Ann Arbor, Michigan, United States of America.
PLoS biology
|August 31, 2023
概括
听觉皮层活动在运动过程中不会被抑制,而是明确地编码与声音一起的运动速度. 这允许在运动期间进行关键的声音处理,增强生存和适应性行为.
科学领域:
- 神经科学是一个神经科学.
- 审计处理 审计处理
- 机车运动 机车运动
背景情况:
- 听觉皮层 (AC) 对于处理声音至关重要,但在运动过程中其活动似乎被抑制.
- 这种在运动过程中抑制外部声音的功能作用尚不清楚.
- 人们争论的是,这是否反映了AC参与度的减少,还是被其他神经计算掩盖了.
研究的目的:
- 为了测试运动过程中减少的声音引起的反应是否是编码运动速度的权衡.
- 调查在运动期间听觉处理的基础的神经机制.
- 为了确定AC是否明确地与声音一起编码移动速度.
主要方法:
- 在行为小鼠中进行神经失活,以评估AC在声音引导运动中的作用.
- 在清醒的小鼠中,对听觉皮层神经群体的双光子成像.
- 在自由移动的老鼠中进行电生理学记录.
主要成果:
- 交流电路对于在行驶过程中以声音为导向的行为至关重要.
- 运动会影响AC神经元的活动,净抑制声音引起的反应.
- 升高的持续交流活动可靠地编码出行速度,压缩动态范围.
- 听觉皮层组合共编码运动速度和声音信息.
- 在老鼠中观察到声音和运动速度的联合编码.
结论:
- 在移动过程中减少的声音引起的反应不是简单的抑制,而是对编码速度的权衡.
- 听觉皮层组合与声音一起明确编码移动速度.
- 这种联合编码支持运动期间的声音感知,这对生存至关重要.
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