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Updated: Jul 17, 2025

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
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在未经治疗的晚期黑色素瘤中使用Bempegaldesleukin加Nivolumab:开放标签,III期PIVOT IO 001试验结果

Adi Diab1, Helen Gogas2, Shahneen Sandhu3

  • 1Melanoma Medical Oncology Department, The University of Texas MD Anderson Cancer Center, Houston, TX.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
|August 31, 2023
PubMed
概括

与单独使用NIVO相比,Bempegaldesleukin (BEMPEG) 加上nivolumab (NIVO) 并没有改善第一线转移性黑色素瘤的结果. 在PIVOT IO 001试验中,组合治疗显示出毒性增加,但未达到初级疗效终点.

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