多次 (前载) 视觉现场测试增加了对绿眼中非常缓慢的平均偏差进展的识别
Jack Phu1, Jeremy Tan2, Michael Kalloniatis3
1School of Optometry and Vision Science, University of New South Wales, Kensington, NSW, Australia; School of Medicine (Optometry), Deakin University, Waurn Ponds, Victoria, Australia; Faculty of Medicine and Health, University of Sydney, NSW, Australia; Centre for Eye Health, UNSW, Sydney, NSW, Australia.
概括
前置视野 (VF) 测试,每次访问执行多个测试,显著改善了对青光眼进展的检测. 这种方法,特别是每6个月间隔的方法,比每次访问一次的单个测试更有效.
科学领域:
- 眼科医生 眼科 眼科
- 玻璃眼研究研究 玻璃眼研究
- 视觉现场测试 视觉现场测试
背景情况:
- 玻璃眼是一种渐进的视神经病变,其特点是视野 (VF) 损失.
- 早期和准确地检测青光眼的进展对于及时干预至关重要.
- 目前的方法在检测缓慢的进展率方面可能存在局限性.
研究的目的:
- 评估前载 (多次) VF测试对检测缓慢渐进型青光瘤中平均偏差 (MD) 变化的影响.
- 为了比较前置加载与单个VF测试在识别青光眼的进展中的有效性.
主要方法:
- 一项计算机模拟研究,涉及1万名模拟基线MD和进展率的患者.
- 模拟VF测试长达10年,包括进展和可变性.
- 独立的变量包括每次访问的VF测试数量 (一对两),VF可靠性,重复测试和随访间隔 (6个月对每年).
主要成果:
- 在10年内,预先装载发现了明显更多的进步者 (62.7%-79.2%),而不是预先装载 (31.0%-36.7%).
- 与每年间隔相比,每六个月的随访提高了检测率.
- 虽然非前期装载检测到一些进展者稍早,但差异在临床上并不显著.
结论:
- 在6个月间进行一次前置VF测试,可以大大提高缓慢进展的绿内障中MD进展的检测率.
- 这种策略提供了一个更敏感的方法,而不是每次访问一次VF测试每年间隔.
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