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Microfluidic Platform with Multiplexed Electronic Detection for Spatial Tracking of Particles
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使用连续控制器的多重数字微流体及其在葡萄糖传感中的应用.

Xinyu Liu1, Jinying Cai1, Wenjia Wang1

  • 1Department of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen 518060, China; Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, Medical School, Shenzhen University, Shenzhen 518060, China.

SLAS technology
|August 31, 2023
PubMed
概括

本研究介绍了使用印刷电路板 (PCB) 控制多个DMF板同时进行数字微流体 (DMF) 的新平台. 这项创新提高了资源有限的环境中具有成本效益的临床诊断的吞吐量.

关键词:
数字微流体学 数字微流体学高吞吐量测试试验法在护理场所进行检测.印刷电路板的使用情况

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科学领域:

  • 生物医学工程 生物医学工程
  • 微流体学 微流体学
  • 诊断 诊断 诊断 诊断

背景情况:

  • 数字微流体 (DMF) 对体外诊断 (IVD) 有价值.
  • 基于印刷电路板 (PCB) 的DMF比基于微型制造的DMF提供了经济优势和仪器兼容性.
  • 目前基于PCB的DMF系统在同时进行滴滴控制方面存在局限性,阻碍了吞吐量和护理点应用.

研究的目的:

  • 开发一个平台,同时控制多个基于PCB的DMF板.
  • 为了证明平台在高通量诊断方面的能力.

主要方法:

  • 开发用于多板控制的集成软件和硬件.
  • 对开发的平台进行严格的可靠性测试.
  • 在基于PCB的DMF系统上应用彩度葡萄糖分析.

主要成果:

  • 成功构建并验证了基于多板PCB的同时DMF控制平台.
  • 证明了高通量色度分析葡萄糖分析的可行性.
  • 该平台可以实现同时操作,显著增加吞吐量.

结论:

  • 开发的基于多板PCB的DMF平台克服了当前系统的吞吐量限制.
  • 这项技术具有显著的潜力,用于低成本,高通量点的护理测试,特别是在资源有限的环境中.
  • 该系统与现有的IVD工具兼容,方便采用.